Skip to main content

ULTRA-DD

Innovative Medicines Initiative LogoEfpia logoEuropean Commission Research and Innovation logo

Search

  • Overview
    • Objectives and disease focus
    • Deliverables
      • Executive Summary 2020 Report
      • Executive Summary 2019 Report
      • Executive Summary 2018 Report
    • Organisation
      • Scientific Committee
      • Leadership
    • Participants
    • News
    • Contact
  • Tissue Platforms
    • Diseases
    • Cell Assay Datasets
  • Probes
    • Chemical Probes
    • Biological probes
  • Antibodies
  • Structures
  • ChromoHub
  • Publications

Targeted protein degradation: expanding the toolbox.

  • Read more about Targeted protein degradation: expanding the toolbox.

Schapira, M., Calabrese, M., Bullock, A., & Crews, C. (2019). Targeted protein degradation: expanding the toolbox. Nature Reviews Drug Discovery, 18(12), 949-963.

A chemical probe of CARM1 alters epigenetic plasticity against breast cancer cell invasion.

  • Read more about A chemical probe of CARM1 alters epigenetic plasticity against breast cancer cell invasion.

Cai, X. C., Zhang, T., Kim, E. J., Jiang, M., Wang, K., Wang, J., … Luo, M. (2019). A chemical probe of CARM1 alters epigenetic plasticity against breast cancer cell invasion. eLife, 8, e47110.

Structural basis for the recognition of non-methylated DNA by the CXXC domain.

  • Read more about Structural basis for the recognition of non-methylated DNA by the CXXC domain.

Liu, K., & Min, J. (2019). Structural Basis for the Recognition of Non-methylated DNA by the CXXC Domain. Journal Of Molecular Biology.

Quinazoline-based anti-virulence compounds selectively target Salmonella PhoP/PhoQ signal transduction system.

  • Read more about Quinazoline-based anti-virulence compounds selectively target Salmonella PhoP/PhoQ signal transduction system.

Carabajal, M., Asquith, C., Laitinen, T., Tizzard, G., Yim, L., Rial, A., ... García Véscovi, E. (2019). Quinazoline-Based Antivirulence Compounds Selectively Target Salmonella PhoP/PhoQ Signal Transduction System. Antimicrobial Agents And Chemotherapy, 64(1).

Lessons from LIMK1 enzymology and their impact on inhibitor design.

  • Read more about Lessons from LIMK1 enzymology and their impact on inhibitor design.

Salah, E., Chatterjee, D., Beltrami, A., Tumber, A., Preuss, F., Canning, P., … Mathea, S. (2019). Lessons from LIMK1 enzymology and their impact on inhibitor design. The Biochemical journal, 476(21), 3197–3209.

Cryo-EM structures of the human glutamine transporter SLC1A5 (ASCT2) in the outward-facing conformation.

  • Read more about Cryo-EM structures of the human glutamine transporter SLC1A5 (ASCT2) in the outward-facing conformation.

Yu, X., Plotnikova, O., Bonin, P. D., Subashi, T. A., McLellan, T. J., Dumlao, D., … Han, S. (2019). Cryo-EM structures of the human glutamine transporter SLC1A5 (ASCT2) in the outward-facing conformation. eLife, 8, e48120.

SETD7 at the heart of chromatin factor interplay.

  • Read more about SETD7 at the heart of chromatin factor interplay.

Barsyte-Lovejoy D. (2019). SETD7 at the heart of chromatin factor interplay. Stem cell investigation, 6, 20.

Fostering open collaboration in drug development for paediatric brain tumours.

  • Read more about Fostering open collaboration in drug development for paediatric brain tumours.

Wong, J. F., Brown, E. J., Williams, E., & Bullock, A. N. (2019). Fostering open collaboration in drug development for paediatric brain tumours. Biochemical Society transactions, 47(5), 1471–1479.

A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function.

  • Read more about A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function.

Fagan, V., Johansson, C., Gileadi, C., Monteiro, O., Dunford, J., Nibhani, R., ... Oppermann, U. (2019). A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function. Journal Of Medicinal Chemistry, 62(20), 9008-9025.

The C-Terminal Domains SnRK2 Box and ABA Box Have a Role in Sugarcane SnRK2s Auto-Activation and Activity.

  • Read more about The C-Terminal Domains SnRK2 Box and ABA Box Have a Role in Sugarcane SnRK2s Auto-Activation and Activity.

Righetto, G. L., Sriranganadane, D., Halabelian, L., Chiodi, C. G., Elkins, J. M., Massirer, K. B., … Couñago, R. M. (2019). The C-Terminal Domains SnRK2 Box and ABA Box Have a Role in Sugarcane SnRK2s Auto-Activation and Activity. Frontiers in plant science, 10, 1105.

Pagination

  • Previous page ‹‹
  • Next page ››
Subscribe to 2019
The ULTRA-DD project is supported by the Innovative Medicines Initiative Joint Undertaking (IMI JU) under grant agreement n° [115766], resources of which are composed of financial contribution from the European Union's Seventh Framework Programme (FP7/2007-2013) and EFPIA companies’ in kind contribution. This website reflects only the author’s views and neither IMI nor the European Commission is liable for any use that may be made of the information contained therein.
This website is licensed under a CC-BY licence | Accessibility