Objectives and disease focus
This partnership, which started on March 1st 2015, comprises Universitites, Hospitals, Pharmaceutical Companies, Biotechs and Disease Foundations working towards:
- Generating protein based research tools (e.g. structures, assays)
- Generating chemical and antibody probes
- Using patient-cell derived assays for target definition and validation
- Making all reagents and knowledge available through Open Source
- Significantly contribute to understanding of complex disease systems
- Promote drug discovery and development
Research tools
- Target Selection
- Protein Production
- Biochemical and Biophysical Assasys
- 3D Structures
- Chemical Biology
- Protein Production
- Antibody Generation
- Functional Proteomics (mass spectrometry)
- Target Selection
- Chemical Biology
Disease focus
Inflammatory diseases that induce bone and cartilage damage:
- Fibrosis (of e.g. hand, lung and liver)
- Ankylosing spondylitis (AS)
- Fibrodysplasia ossificans progressiva (FOP, stone man syndrome)
Systemic inflammatory autoimmune diseases (SIADs) with increased common co-morbidities such as cancer and cardiovascular disease:
- Systemic Lupus Erythematosus (SLE)
- Idiopathic myositis
- Systemic sclerosis (SSc)
- Sjogren´s syndrome (SS)